Growth HormonePrices may be stale · 8d ago

Sermorelin

Sermorelin is a synthetic analogue of the first 29 amino acids of growth hormone releasing hormone. It was once approved as Geref for paediatric use but was withdrawn from the United States market in 2008, and now circulates mainly through compounding pharmacies.

Lowest cost / mg: $3.00/mg; at Amino Club
Suppliers listed: 46
In stock: 61 of 62; listings
COA reports: 44

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61 listings · Sermorelin

Nura PeptideFeatured partner placement, shown above the price ranking
In stock5 mg · 3 vialsseen 1w ago
$108.00
$135.00$7.20/mg-20%
PEPLOOKUP
Amino ClubLowest $/mg
In stock10mgseen 7w ago
$23.99
$29.99$2.40/mg-20%
PRODUCTS
Biologix Labs
In stock2mgseen 5w ago
$17.99
$19.99$9.00/mg-10%
PEPLOOKUP
HLX Labs
In stock5mgseen 7w ago
$26.99
$29.99$5.40/mg-10%
products
Kalyx Labs
In stock5mgseen 7w ago
$22.49
$29.99$4.50/mg-25%
adamdan
Peppy&Me
In stock10mgseen 7w ago
$27.00
$30.00$2.70/mg-10%
peplookup
Aminexa
In stock10mgseen 7w ago
$31.50
$35.00$3.15/mg-10%
products
Rejuven8 Peptides
In stock5mgseen 7w ago
$29.75
$35.00$5.95/mg-15%
adam15
Peptide Giants
In stock5mgseen 7w ago
$31.50
$35.00$6.30/mg-10%
adamdan
Peptide Titans
In stock5mgseen 7w ago
$35.99
$39.99$7.20/mg-10%
products
Cielo Crew
In stock10mgseen 7w ago
$32.00
$40.00$3.20/mg-20%
PEPTOOKUP
Pure Peptides
In stock5mgseen 4w ago
$42.00
$8.40/mg
Eon Peptides
In stock10mgseen 2w ago
$38.25
$42.50$3.83/mg-10%
PEPLOOKUP
GenX
In stock5mgseen 7w ago
$38.70
$43.00$7.74/mg-10%
peplookup
Ameano Peptides
In stock5mgseen 7w ago
$39.60
$44.00$7.92/mg-10%
PEPLOOKUP
Nextgen Peptides
In stock10mgseen 2w ago
$45.00
$4.50/mg
Elite Edge Biotech
In stock10mgseen 7w ago
$44.10
$49.00$4.41/mg-10%
10ADAMDAN668
AminoVault
In stock5mgseen 7w ago
$42.27
$49.73$8.45/mg-15%
PEPLOOKUP
Disguised Alpha
In stock5mgseen 4w ago
$44.99
$49.99$9.00/mg-10%
PEPLOOKUP
Palmetto Peptides
In stock5mgseen 7w ago
$45.00
$50.00$9.00/mg-10%
PRODUCTS

Overview

What is Sermorelin?

GH Support
Sleep Quality
Recovery
Body Composition

What the research reports

Reported benefits of Sermorelin

Outcomes described across the published Sermorelin literature and ongoing study. Read each as research context rather than a promised personal result.

01
Physiological GH pulse release
Acts on the pituitary as a GHRH analogue, so release follows the body's own pulsatile pattern rather than overriding it. Reported in research settings.
02
IGF-1 elevation in cohorts
A 2017 cohort of 14 hypogonadal men on testosterone reported raised serum IGF-1 after growth hormone secretagogue therapy. Reported in research settings.
03
Circadian GH pulse context
Natural growth hormone release follows a pulsatile pattern concentrated overnight in humans. This physiological pattern is the basis for the drug class's mechanism, though no controlled trial on this page has measured outcomes tied to timing specifically.
04
Short acting release profile
The 10 to 20 minute half-life means exposure is brief, which is often presented as a safety argument for this class. Described in the research record.
05
Long clinical familiarity
The molecule has been in clinical use since the 1980s, giving prescribers a longer familiarity than most research peptides. Reported in research settings.

Clinical evidence

Clinical evidence for Sermorelin

The published record for Sermorelin, labeled by strength so you can see what is settled and what is emerging.

IGF-1 cohort study 2017 men

A cohort of 14 hypogonadal men on testosterone reported raised serum IGF-1 levels after growth hormone secretagogue therapy including sermorelin over 134 days. Reported in the cited paper.

Source

Adult GH insufficiency review

A 2006 review argued sermorelin may be a better approach to adult onset growth hormone insufficiency than direct growth hormone replacement. Reported in the cited paper.

Source

Falsified injectables report

A 2016 review of seizures across Europe found sermorelin among falsified biopharmaceutical injectables, a supply chain warning rather than efficacy data. Reported in the cited paper.

Source

Interactions

How Sermorelin pairs with other peptides

MK-677 oral: Stacking growth hormone secretagogues is studied as increasing IGF-1 and insulin resistance risk in the research literature. No published data establishes a safe combined dosing approach, consult the primary literature or a qualified professional before combining research compounds.
Ipamorelin: GHRH analogue plus ghrelin mimetic amplifies the pulse, but also raises total IGF-1 exposure.
Tesamorelin: Both are GHRH analogues on the same receptor, so combining duplicates one mechanism without benefit.
Corticosteroids: Steroid therapy can blunt the pituitary response and reduce the growth hormone pulse achieved.

Questions

Frequently asked questions.

What is Sermorelin?

Sermorelin is a synthetic growth hormone-releasing hormone (GHRH) analog, representing the first 29 amino acids of the full GHRH sequence, studied for its ability to stimulate the pituitary gland's own growth hormone release.

Does Sermorelin help build muscle?

Sermorelin stimulates the body's natural GH release rather than directly building muscle. Any downstream effect on body composition would depend on the broader GH/IGF-1 axis, not a direct muscle-building mechanism.

Sermorelin vs Tesamorelin or Ipamorelin, what's the difference?

Sermorelin and Tesamorelin are both GHRH analogs, but Tesamorelin has FDA approval and a large clinical trial base for a specific indication, while Sermorelin does not. Ipamorelin works through an entirely different receptor (the ghrelin receptor, not GHRH). Compare Tesamorelin pricing.

Does Sermorelin research include dosage information?

PepLookup doesn't publish dosing guidance for any compound. Check the Evidence section on this page for the actual published research.

Does PepLookup sell Sermorelin?

No. PepLookup is a comparison tool. We list publicly published prices from suppliers so they can be compared side by side. Every order is placed on the supplier's own site.

Sermorelin

Lowest cost / mg

$3.00/mg

at Amino Club

Suppliers listed

In stock

61 of 62

listings

COA reports

What is Sermorelin?

GH Support

Sleep Quality

Recovery

Body Composition

Reported benefits of Sermorelin

Outcomes described across the published Sermorelin literature and ongoing study. Read each as research context rather than a promised personal result.

Physiological GH pulse release

Acts on the pituitary as a GHRH analogue, so release follows the body's own pulsatile pattern rather than overriding it. Reported in research settings.

IGF-1 elevation in cohorts

A 2017 cohort of 14 hypogonadal men on testosterone reported raised serum IGF-1 after growth hormone secretagogue therapy. Reported in research settings.

Circadian GH pulse context

Natural growth hormone release follows a pulsatile pattern concentrated overnight in humans. This physiological pattern is the basis for the drug class's mechanism, though no controlled trial on this page has measured outcomes tied to timing specifically.

Short acting release profile

The 10 to 20 minute half-life means exposure is brief, which is often presented as a safety argument for this class. Described in the research record.

Long clinical familiarity

The molecule has been in clinical use since the 1980s, giving prescribers a longer familiarity than most research peptides. Reported in research settings.

Clinical evidence for Sermorelin

The published record for Sermorelin, labeled by strength so you can see what is settled and what is emerging.

IGF-1 cohort study 2017 men

A cohort of 14 hypogonadal men on testosterone reported raised serum IGF-1 levels after growth hormone secretagogue therapy including sermorelin over 134 days. Reported in the cited paper.

Source

Adult GH insufficiency review

A 2006 review argued sermorelin may be a better approach to adult onset growth hormone insufficiency than direct growth hormone replacement. Reported in the cited paper.

Source

Falsified injectables report

A 2016 review of seizures across Europe found sermorelin among falsified biopharmaceutical injectables, a supply chain warning rather than efficacy data. Reported in the cited paper.

Source

How Sermorelin pairs with other peptides

MK-677 oral

Stacking growth hormone secretagogues is studied as increasing IGF-1 and insulin resistance risk in the research literature. No published data establishes a safe combined dosing approach, consult the primary literature or a qualified professional before combining research compounds.

Ipamorelin

GHRH analogue plus ghrelin mimetic amplifies the pulse, but also raises total IGF-1 exposure.

Tesamorelin

Both are GHRH analogues on the same receptor, so combining duplicates one mechanism without benefit.

Corticosteroids

Steroid therapy can blunt the pituitary response and reduce the growth hormone pulse achieved.