Phenazepam comparison, 2014
A randomised trial in 60 patients with anxiety disorders reported anxiolytic effect comparable to phenazepam with improved tolerability over the study period. Reported in the cited paper.
SourceResearch Use Only. Products listed are not for human or animal consumption. Statements have not been evaluated by the FDA.View full disclaimers →
Selank is a synthetic heptapeptide built from the tuftsin fragment with additional amino acids for stability. Developed in Russia and registered there as an anxiolytic, it is studied for anxiety reduction without the sedation associated with benzodiazepines.
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Overview
Selank is a synthetic heptapeptide built from the tuftsin fragment with additional amino acids for stability. Developed in Russia and registered there as an anxiolytic, it is studied for anxiety reduction without the sedation associated with benzodiazepines.
What the research reports
Outcomes described across the published Selank literature and ongoing study. Read each as research context rather than a promised personal result.
Anxiolytic effect in trials
Russian randomised trials in patients with anxiety disorders reported effects comparable to phenazepam with better tolerability. Reported in research settings.
Reduced sedation in study
Unlike benzodiazepines the published work does not report drowsiness, which is the main practical argument for this peptide. Reported in research settings.
Benzodiazepine side effects
A 2015 trial found combining selank with phenazepam reduced benzodiazepine related side effects while keeping anxiolytic efficacy. Reported in research settings.
Antiasthenic trial activity
A 2008 trial reported anxiolytic effects similar to medazepam alongside additional antiasthenic effects in generalised anxiety. Reported in research settings.
Immune signalling effects
Derived from tuftsin, and a case series reported modulation of the Th1 and Th2 cytokine balance over 14 days of dosing. Reported in research settings.
Dosage and protocol
Protocols use 200 to 400 mcg daily intranasally, split across one to three doses, across a 14 to 21 day period. These figures describe research protocols rather than a personal regimen.
Clinical evidence
The published Selank record, labeled by strength so you can see what is settled and what is still emerging.
A randomised trial in 60 patients with anxiety disorders reported anxiolytic effect comparable to phenazepam with improved tolerability over the study period. Reported in the cited paper.
SourceA 2008 randomised trial in 62 patients reported anxiolytic effects similar to medazepam, with additional antiasthenic effects in neurasthenia. Reported in the cited paper.
SourceA 2015 randomised trial in 70 patients found combining selank with phenazepam reduced benzodiazepine related side effects while retaining efficacy. Reported in the cited paper.
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