Postoperative ileus RCT work
A 2014 phase 2 randomised trial in 114 bowel resection patients found ipamorelin well tolerated but showed no significant difference against placebo. Reported in the cited paper.
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Growth Hormone
Ipamorelin
Ipamorelin is a selective pentapeptide growth hormone secretagogue that acts on the ghrelin receptor. It is described as one of the cleanest peptides in its class because it raises growth hormone with little effect on cortisol or prolactin levels.
- Lowest cost / mg
- $2.52/mg
- at Peptide Labs Inc
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Overview
What is Ipamorelin?
Ipamorelin is a selective pentapeptide growth hormone secretagogue that acts on the ghrelin receptor. It is described as one of the cleanest peptides in its class because it raises growth hormone with little effect on cortisol or prolactin levels.
- GH Support
- Recovery
- Sleep Quality
- Body Composition
What the research reports
Reported benefits of Ipamorelin
Outcomes described across the published Ipamorelin literature and ongoing study. Read each as research context rather than a promised personal result.
- 01
Selective clean GH release
Stimulates growth hormone through the ghrelin receptor with minimal effect on cortisol and prolactin, unlike older peptides in the same secretagogue class.
- 02
Favourable tolerability data
Human studies reported good tolerability, including a phase 2 trial where the peptide was well tolerated across a seven day dosing period. Reported in research settings.
- 03
Predictable pharmacokinetics
A 1999 study in 40 volunteers reported dose proportional kinetics, potent growth hormone stimulation and a half-life of about two hours. Reported in research settings.
- 04
Recovery research interest
Used in recovery protocols on the basis of the growth hormone axis, though no published human trial has measured recovery outcomes. Reported in research settings.
- 05
Sleep and body composition
Commonly studied for nighttime dosing to align with natural growth hormone pulses, again without controlled human outcome data. Reported in research settings.
Dosage and protocol
How Ipamorelin is typically studied
Research protocols use 100 to 300 mcg per injection, one to three times daily, across 8 to 12 week cycles. The half-life is approximately two hours after subcutaneous administration.
- Route
- Subcutaneous injection
- Example range
- 200-300 mcg
- Frequency
- Two to three times daily
- Timing
- Empty stomach, 30 min before food. Waking, training or bedtime.
Clinical evidence
Clinical evidence for Ipamorelin
The published record for Ipamorelin, labeled by strength so you can see what is settled and what is emerging.
Pharmacokinetic study, 1999
A phase 1 dose escalation study in 40 human volunteers reported dose proportional kinetics, a two hour half-life and potent growth hormone stimulation. Reported in the cited paper.
SourceUrinary detection study work
A 2015 paper measured urinary metabolites after nasal dosing of several growth hormone releasing peptides, work aimed at anti-doping detection windows. Reported in the cited paper.
SourceInteractions
How Ipamorelin pairs with other peptides
- CJC-1295 blend
- Synergistic for GH release. A GHRH analogue plus a ghrelin mimetic amplifies the pulse through two pathways.
- BPC-157 peptide
- No known negative interaction. The two are often used together and act on separate primary targets.
- MK-677 oral
- Stacking growth hormone secretagogues raises IGF-1 and insulin resistance risk. Lower doses are advised.
- Sermorelin
- Both raise growth hormone. Combining two secretagogues increases the risk of excessive IGF-1 levels.
Questions
Frequently asked questions.
What is Ipamorelin?
Ipamorelin is a peptide compound used in research settings. It is commonly studied for its role in growth hormone, and many researchers compare supplier quality, purity, and testing data before purchasing.
What are the research benefits of Ipamorelin?
Ipamorelin is often evaluated for its potential influence on signaling pathways, recovery support, and targeted research applications. Research interest varies by peptide, formulation, and study design, so buyers typically review purity, dose, and independent lab verification before choosing a source.
How does Ipamorelin work?
Like other research peptides, Ipamorelin is typically studied for how it interacts with specific biological pathways and receptor systems. In practice, the way it is formulated, dosed, and tested matters as much as the compound itself, which is why verified suppliers and transparent COAs are important.
Is Ipamorelin for research use only?
Yes, products like Ipamorelin are generally intended for research, laboratory, or educational use and are not marketed as approved human therapeutics. Always follow local laws, lab safety practices, and institutional requirements before handling or studying any peptide.
What should I look for before buying Ipamorelin?
Key checks include verified COA data, peptide form and concentration, supplier reputation, stock status, and cost per mg. Comparing pricing and testing records side-by-side helps reduce the risk of buying an under-tested or misrepresented product.
