Chronic insomnia trial, 1987
A randomised trial in 14 patients with severe chronic insomnia reported improved night sleep efficiency and daytime alertness over seven nights of dosing. Reported in the cited paper.
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SleepRecovery
DSIP
DSIP, or delta sleep-inducing peptide, is a neuropeptide first isolated from rabbit cerebral venous blood during slow wave sleep. It has been studied for sleep architecture and stress response, with controlled trials producing mixed and largely negative results.
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- $2.00/mg
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Overview
What is DSIP?
DSIP, or delta sleep-inducing peptide, is a neuropeptide first isolated from rabbit cerebral venous blood during slow wave sleep. It has been studied for sleep architecture and stress response, with controlled trials producing mixed and largely negative results.
- Sleep Support
- Stress Recovery
- Relaxation
What the research reports
Reported benefits of DSIP
Outcomes described across the published DSIP literature and ongoing study. Read each as research context rather than a promised personal result.
- 01
Sleep architecture research
Studied for effects on delta wave sleep and sleep structure, which is the origin of the peptide's name and its research interest. Reported in research settings.
- 02
Short half-life exposure note
The 15 minute half-life means exposure is brief, which also explains why effects are reported as inconsistent across studies. Reported in research settings.
- 03
Insomnia clinical study work
Several 1980s and 1990s trials tested it in chronic insomnia, with one reporting improved sleep efficiency and daytime alertness. Reported in research settings.
- 04
Stress response study record
Proposed as a modulator of stress hormones, although a controlled trial found no effect on ACTH or cortisol secretion. Described in the research record.
- 05
Historical research value
The peptide has a long study record from the 1970s onward, useful context even though the field largely moved on. Noted across the published research record.
Dosage and protocol
How DSIP is typically studied
Protocols use 100 to 300 mcg before bed, often as a course of daily injections over 5 to 14 days. The half-life is about 15 minutes. Figures describe study protocols, not a personal regimen.
- Route
- Subcutaneous injection
- Example range
- 100-200 mcg
- Frequency
- Once daily before bed
- Timing
- Thirty to sixty minutes before intended sleep. Short half-life matters.
Clinical evidence
DSIP clinical evidence summary
The published DSIP record, labeled by strength so you can see what is settled and what is still emerging.
Double blind insomnia study
A 1992 randomised trial in 16 chronic insomnia patients found only weak effects on sleep efficiency and latency, judged unlikely to offer real therapeutic benefit.
SourceStress hormone trial, 1995
A randomised study in 15 participants reported that the peptide did not affect ACTH or cortisol secretion in response to CRH or to meals. Reported in the cited paper.
SourceInteractions
How DSIP pairs with other peptides
- Sedative drugs
- No published interaction data. Combining with prescription sleep medicine needs clinical oversight.
- Alcohol use
- Alcohol disrupts sleep architecture, working against the outcome this peptide is studied for.
- Melatonin use
- Both are studied for sleep by different mechanisms, with no published data on combined use.
- Anaesthetic agents
- A trial found the peptide reduced anaesthetic depth during isoflurane anaesthesia, the opposite of sedation.
Questions
Frequently asked questions.
What is DSIP?
DSIP is a peptide compound used in research settings. It is commonly studied for its role in sleep, recovery, and many researchers compare supplier quality, purity, and testing data before purchasing.
What are the research benefits of DSIP?
DSIP is often evaluated for its potential influence on signaling pathways, recovery support, and targeted research applications. Research interest varies by peptide, formulation, and study design, so buyers typically review purity, dose, and independent lab verification before choosing a source.
How does DSIP work?
Like other research peptides, DSIP is typically studied for how it interacts with specific biological pathways and receptor systems. In practice, the way it is formulated, dosed, and tested matters as much as the compound itself, which is why verified suppliers and transparent COAs are important.
Is DSIP for research use only?
Yes, products like DSIP are generally intended for research, laboratory, or educational use and are not marketed as approved human therapeutics. Always follow local laws, lab safety practices, and institutional requirements before handling or studying any peptide.
What should I look for before buying DSIP?
Key checks include verified COA data, peptide form and concentration, supplier reputation, stock status, and cost per mg. Comparing pricing and testing records side-by-side helps reduce the risk of buying an under-tested or misrepresented product.
