Laser resurfacing RCT, 2006
In a randomised trial of 13 patients, topical copper tripeptide after CO2 laser resurfacing produced no significant reduction in redness or wrinkles despite better satisfaction.
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Anti-AgingSkin and Hair
GHK-Cu
GHK-Cu is a copper bound tripeptide studied for collagen synthesis, wound healing, skin rejuvenation and hair follicle support. It is used topically in cosmetic formulations and by injection in research settings, where the copper complex carries its own cautions.
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- $0.14/mg
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1 listing · GHK-Cu · 25mg
In stock25mgseen 7d ago
Overview
What is GHK-Cu?
GHK-Cu is a copper bound tripeptide studied for collagen synthesis, wound healing, skin rejuvenation and hair follicle support. It is used topically in cosmetic formulations and by injection in research settings, where the copper complex carries its own cautions.
- Skin Rejuvenation
- Collagen Support
- Wound Healing
- Hair Support
What the research reports
Reported benefits of GHK-Cu
Outcomes described across the published GHK-Cu literature and ongoing study. Read each as research context rather than a promised personal result.
- 01
Collagen and elastin support
Studied for stimulating collagen and glycosaminoglycan synthesis, which is the basis for its long use in cosmetic skin formulations. Reported in research settings.
- 02
Wound healing study results
Animal and cell work reports faster wound closure and tissue remodelling, with copper acting as a cofactor for lysyl oxidase and other repair enzymes.
- 03
Skin rejuvenation study work
A small randomised trial of 13 patients found no measurable change in redness or wrinkles after CO2 laser resurfacing, although patient satisfaction scores improved.
- 04
Antioxidant activity study
Preclinical work reports reduced oxidative stress, including studies in lung inflammation models that point to peroxiredoxin 6 involvement. Reported in research settings.
- 05
Hair follicle study support
Copper peptides are studied for dermal papilla activity and follicle support, mostly in cell culture rather than controlled human trials. Reported in research settings.
Dosage and protocol
How GHK-Cu is typically studied
Topical formulations use 1 to 3 percent concentrations applied to clean skin. Injection protocols report 1 to 4 mg daily with a short half-life of minutes to hours, refrigerate after mixing.
- Route
- Topical or injection
- Example range
- 1-2 mg
- Frequency
- Once or twice daily
- Timing
- Topical on clean skin morning or night. Injection once or twice daily.
Clinical evidence
GHK-Cu clinical evidence summary
The published GHK-Cu record, labeled by strength so you can see what is settled and what is still emerging.
ACL healing in rats, 2015
A 72 animal study of ACL reconstruction found knee laxity improved at six weeks after surgery with GHK-Cu, but the benefit did not persist to twelve weeks. Reported in the cited paper.
SourceLung fibrosis model, 2024
In a silicosis model the tripeptide reduced lung inflammation and fibrosis, an effect the authors attributed to peroxiredoxin 6 and lower oxidative stress. Reported in the cited paper.
SourceInteractions
How GHK-Cu pairs with other peptides
- BPC-157 peptide
- Synergistic for tissue remodelling. Both support wound healing through separate biological mechanisms.
- TB-500 peptide
- Frequently combined in repair blends, adding collagen signalling to actin mediated cell migration.
- Vitamin C serums
- Direct layering with strong acids or ascorbic acid can destabilise the copper complex in topical use.
- AHK-Cu peptide
- Both are copper peptides, so combining them raises total copper exposure on the same application area.
Questions
Frequently asked questions.
What is GHK-Cu?
GHK-Cu is a peptide compound used in research settings. It is commonly studied for its role in anti-aging, skin and hair, and many researchers compare supplier quality, purity, and testing data before purchasing.
What are the research benefits of GHK-Cu?
GHK-Cu is often evaluated for its potential influence on signaling pathways, recovery support, and targeted research applications. Research interest varies by peptide, formulation, and study design, so buyers typically review purity, dose, and independent lab verification before choosing a source.
How does GHK-Cu work?
Like other research peptides, GHK-Cu is typically studied for how it interacts with specific biological pathways and receptor systems. In practice, the way it is formulated, dosed, and tested matters as much as the compound itself, which is why verified suppliers and transparent COAs are important.
Is GHK-Cu for research use only?
Yes, products like GHK-Cu are generally intended for research, laboratory, or educational use and are not marketed as approved human therapeutics. Always follow local laws, lab safety practices, and institutional requirements before handling or studying any peptide.
What should I look for before buying GHK-Cu?
Key checks include verified COA data, peptide form and concentration, supplier reputation, stock status, and cost per mg. Comparing pricing and testing records side-by-side helps reduce the risk of buying an under-tested or misrepresented product.
